|
|
| Line 1: |
Line 1: |
| ''De Burgh Daly M(1986) Interactions between respiration and circulation. Handbook of Physiology, section 3: 529–594.'' | | ''De Burgh Daly M(1986) Interactions between respiration and circulation. Handbook of Physiology, section 3: 529–594.'' |
|
| |
|
| '''[http://ajpheart.physiology.org/content/ajpheart/234/3/H293.full.pdf Link to Article]''' | | '''[http://onlinelibrary.wiley.com/doi/10.1002/cphy.cp030216/full Link to Article]''' |
|
| |
|
| '''Abstract:''' The carotid bodies were stimulated in the anesthetized pig-tailed macaque monkey (Macaca nemestrina) using i) brief injections of cyanide or CO2-equilibrated bicarbonate solution into a common carotid artery, and ii) longer perfusion with hypoxic hypercapnic blood in vascularly isolated chemoreceptor preparations. In spontaneously breathing animals, brief stimulations of the chemoreceptors consistently caused an increase in pulmonary ventilation, bradycardia, and an increase in femoral vascular resistance. When the same chemoreceptor stimulus was superimposed during the apneic period, reflexly evoked by stimulating either the central ends of the superior laryngeal nerves or the nasopharynx, the respiratory stimulation was absent or minimal, but the bradycardia and vasconstriction were greatly enhanced and exceeded the summed responses of separate stimulation of the chemoreceptors and one or the other of the upper-airways inputs. With sustained stimulation of the carotid bodies, hyperventilation, tachycardia, and femoral vasodilatation occurred due to overriding respiratory mechanisms. When superior laryngeal nerve stimulation was superimposed on this response, apnea occurred and tachycardia was reversed to bradycardia, and femoral vascular resistance increased above resting level. The interaction of autonomic responses resulting from chemoreceptor stimulation and from increases in the upper-airways inputs are qualitatively similar in the monkey and in subprimate species. Those involving specifically cardioinhibitory vagal responses are, in part at least, dependent on mechanisms related to the concomitant changes in respiration. | | '''Abstract:''' |
|
| |
|
| | | '''Keywords:''' |
| '''Keywords:''' chemoreceptors, heart rate, nasopharynx, superior laryngeal nerve, sympathetic constrictors, vagus | |
|
| |
|
| =Context= | | =Context= |
|
| |
|
| =Comments= | | =Comments= |
Revision as of 21:45, 17 July 2017
De Burgh Daly M(1986) Interactions between respiration and circulation. Handbook of Physiology, section 3: 529–594.
Link to Article
Abstract:
Keywords:
Context