Recurring discharge patterns in multiple spike trains
Frostig RD, Frysinger RC, and Harper RM(1990) Recurring discharge patterns in multiple spike trains. II. Application in forebrain areas related to cardiac and respiratory control during different sleep-waking states. Biol Cybern 62:6 495–502.
Abstract: Simultaneously recorded spike trains were obtained using microwire bundles from unrestrained, drug-free cats during different sleep-waking states in forebrain areas associated with cardiac and respiratory activity. Cardiac and respiratory activity was simultaneously recorded with the spike trains. We applied the recurring discharge patterns detection procedure described in a companion paper (Frostig et al. 1990) to the spike and cardiorespiratory trains. The pattern detection procedure was applied to detect only precise (in time and structure) recurring patterns. Recurring discharge patterns were detected in all simultaneously recorded groups. Recurring discharge patterns were composed of up to ten spikes per pattern and involved up to four simultaneously recorded spike trains. Fourty-two percent of the recurring patterns contained cardiac and/or respiratory events in addition to neuronal spikes. When patterns were compared over different sleep-waking states it was found the the same units produced different patterns in different states, that patterns were significantly more compact in time during quiet sleep, and that changes in the discharge rates accompanying changes in sleep-waking states were not correlated with changes in pattern rate.
Context
- Study addresses the involvement of motifs of cortical neuron activity in driving autonomic behaviors. Using extracellular recordings from cat, treats respiration and heartbeat as binary events. Using a motif detection method published separately, searches for motifs in neuronal spike trains and cardiac and respiratory activity. Finds that 42% of identified trains were synchronized with breathing or heartbeat. Such trains were more common in REM sleep than in waking or quiet sleep.