From mystery to prevention: Sudden unexpected death in epilepsy, time to move on
Nashef L (1999) From mystery to prevention: Sudden unexpected death in epilepsy, time to move on. J Neurol Neurosurg Psychiatry p. 427.
First Paragraph: This noteworthy paper of Kloster and Engelskohn in this issue (pp 439–44) supports an important hypothesis in relation to the cause of sudden unexpected death in epilepsy (SUDEP)—namely, that SUDEP is largely seizure related. Their finding of a preponderance of the prone position of the body is also of interest and may have a bear- ing on proposed mechanisms as well as the potential for the prevention of these deaths.
- Comment on Kloster and Engelskjøn addresses methodological issues such as problems using non-SUDEP epilepsy deaths as a control group, as these are largely symptomatic cases. Comments on the finding of greater-than-chance likelihood of being prone as increasing the risk of suffocation.