Difference between revisions of "Respiratory arrest from seizure discharges in the limbic system"

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'''[https://jamanetwork.com/journals/jamaneurology/fullarticle/568296 Link to Article]'''
 
'''[https://jamanetwork.com/journals/jamaneurology/fullarticle/568296 Link to Article]'''
  
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'''Abstract:''' In 1899, Hughlings Jackson1 described respiratory arrest as part of the seizure pattern in a patient whose attacks, included sucking movements in addition to olfactory and gustatory sensations. He classified these seizres as uncinate fits because of his own clinical and pathological observations and because he was influenced by the previous experimental work of Spencer2 in 1894. In several species of animals, Spencer consistently produced expiratory apnea by faradic stimuli applied near the uncus. Since then, a large body of experimental evidence has accumulated which shows that respiratory arrest can occur in the experimental animal and in man when a number of areas in the cerebral hemispheres are stimulated, both electrically and mechanically. The effects on respiration are variable and depend upon the species of animal, the anesthetic used, the type of stimulus, and structure stimulated. Arrest of respiration in expiration often occurs when the following structures
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'''Abstract:''' (Summary) Electrical stimulation to and seizure discharges in the limbic system are capable of producing respiratory arrest usually of less than one minute in duration. Such apnea has been previously reported mostly as expiratory arrest. During a depth stimulation study, when stimuli were applied in or near the left amygdaloid nucleus, our patient had either inspiratory or expiratory arrest depending upon the phase of respiration during which stimuli were applied. The duration of arrest corresponded closely to the duration of the after-discharge. A patient with temporal lobe epilepsy is presented who has had nine episodes of severe respiratory insufficiency not associated with grand mal seizures. The last three of these necessitated the use of a respirator. The hypothesis is advanced that this apnea represents a seizure phenomenon. During one episode, an unusual low-voltage EEG with 6 to 14/sec spindle-like activity was recorded similar to recordings heretofore obtained from animals during experimental anoxia.
  
 
=Context=
 
=Context=
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For context see [[Respiratory modulation of neuronal discharge in the central nucleus of the amygdala during sleep and waking states|Zhang et al., 1986]].
  
 
=Comments=
 
=Comments=

Revision as of 22:03, 25 August 2018

Nelson DA and Ray CD (1968) Respiratory arrest from seizure discharges in limbic system. Report of cases. Arch Neurol 19:2 199–207.

Link to Article

Abstract: (Summary) Electrical stimulation to and seizure discharges in the limbic system are capable of producing respiratory arrest usually of less than one minute in duration. Such apnea has been previously reported mostly as expiratory arrest. During a depth stimulation study, when stimuli were applied in or near the left amygdaloid nucleus, our patient had either inspiratory or expiratory arrest depending upon the phase of respiration during which stimuli were applied. The duration of arrest corresponded closely to the duration of the after-discharge. A patient with temporal lobe epilepsy is presented who has had nine episodes of severe respiratory insufficiency not associated with grand mal seizures. The last three of these necessitated the use of a respirator. The hypothesis is advanced that this apnea represents a seizure phenomenon. During one episode, an unusual low-voltage EEG with 6 to 14/sec spindle-like activity was recorded similar to recordings heretofore obtained from animals during experimental anoxia.

Context

For context see Zhang et al., 1986.

Comments

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