Difference between revisions of "Welcome"

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*Glasscock E, Yoo JW, Chen TT, Klassen TL, and Noebels JL (2010): [[Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy]]
 
*Glasscock E, Yoo JW, Chen TT, Klassen TL, and Noebels JL (2010): [[Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy]]
 
*Goldman AM, Behr ER, Semsarian C, et al. (2016): [[Sudden unexpected death in epilepsy genetics: Molecular diagnostics and prevention]]
 
*Goldman AM, Behr ER, Semsarian C, et al. (2016): [[Sudden unexpected death in epilepsy genetics: Molecular diagnostics and prevention]]
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*Goldman AM, Glasscock E, Yoo J, et al. (2009): [[Arrhythmia in heart and brain: KCNQ1 mutations link epilepsy and sudden unexplained death]]
 
*Gomes RA, Kesrouani S, Cruz J, Silva AL, Henriques TMG, Albuquerque Md, Arida RM, Sonoda EYF, Cysneiros RM, Terra VC et al. (2009): [[Is there something special about cardiovascular abnormalities and sudden unexpected death in epilepsy among patients with chronic renal insufficiency in regular hemodialysis program?]]
 
*Gomes RA, Kesrouani S, Cruz J, Silva AL, Henriques TMG, Albuquerque Md, Arida RM, Sonoda EYF, Cysneiros RM, Terra VC et al. (2009): [[Is there something special about cardiovascular abnormalities and sudden unexpected death in epilepsy among patients with chronic renal insufficiency in regular hemodialysis program?]]
 
*González Martínez F, Navarro Gutiérrez S, de León Belmar JJ, and Valero Serrano B (2005): [[Electrocardiographic disorders associated to recent onset epilepsy]]
 
*González Martínez F, Navarro Gutiérrez S, de León Belmar JJ, and Valero Serrano B (2005): [[Electrocardiographic disorders associated to recent onset epilepsy]]

Revision as of 19:07, 9 July 2018


An increased risk of sudden death has been reported in patients with epilepsy since the late 1800s, and possibly much earlier (DeToledo et al., 1999; Doherty, 2004). Since the 1990s sudden unexpected (or unexplained) death in epilepsy (SUDEP) has received increasing attention and been recognized as more widespread than previously believed. Despite the increase in awareness, “systematic well funded research remains limited. The medical literature contains much repetition, with effort spent on re-analysing data with substantial methodological limitations,” (Tomson et al., 2008). There is a need for better clinical and basic science studies and improved epidemiological data, and there is also a need for increased knowledge of the findings already obtained, and how they interrelate.

This wiki exists to harness the collective knowledge of the worldwide SUDEP research community in the hope of focusing and accelerating the effort to better understand and more effectively prevent SUDEP. A massive literature on sudden death in epilepsy and closely related phenomena exists, with many studies having considerable overlap. Many isolated case reports have been published, and considering them collectively increases their informative power. Users of this tool can add entries for articles including links to the articles themselves, contribute to the discussion of articles, add links to the entries on related articles, or post comments. Comparing and contrasting research findings in this way can highlight where open questions exist and potentially target future investigation more effectively. The ultimate aim is better mechanistic insight into the process, which has the potential to reduce SUDEP deaths.

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