Difference between revisions of "Welcome"

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*Stein PK and Kleiger RE (1999): [[Insights from the study of heart rate variability]]
 
*Stein PK and Kleiger RE (1999): [[Insights from the study of heart rate variability]]
 
*Stemper B, Devinsky O, Haendl T, Welsch G, and Hilz MJ (2008): [[Effects of vagus nerve stimulation on cardiovascular regulation in patients with epilepsy]]
 
*Stemper B, Devinsky O, Haendl T, Welsch G, and Hilz MJ (2008): [[Effects of vagus nerve stimulation on cardiovascular regulation in patients with epilepsy]]
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*Stewart M, Kollmar R, Nakase K, et al. (2017): [[Obstructive apnea due to laryngospasm links ictal to postictal events in SUDEP cases and offers practical biomarkers for review of past cases and prevention of new ones]]
 
*Stokes W (1846): [[Observations on some cases of permanently slow pulse]]
 
*Stokes W (1846): [[Observations on some cases of permanently slow pulse]]
 
*Stöllberger C and Finsterer J (2004): [[Cardiorespiratory findings in sudden unexplained/unexpected death in epilepsy (SUDEP)]]
 
*Stöllberger C and Finsterer J (2004): [[Cardiorespiratory findings in sudden unexplained/unexpected death in epilepsy (SUDEP)]]

Revision as of 15:54, 9 July 2018


An increased risk of sudden death has been reported in patients with epilepsy since the late 1800s, and possibly much earlier (DeToledo et al., 1999; Doherty, 2004). Since the 1990s sudden unexpected (or unexplained) death in epilepsy (SUDEP) has received increasing attention and been recognized as more widespread than previously believed. Despite the increase in awareness, “systematic well funded research remains limited. The medical literature contains much repetition, with effort spent on re-analysing data with substantial methodological limitations,” (Tomson et al., 2008). There is a need for better clinical and basic science studies and improved epidemiological data, and there is also a need for increased knowledge of the findings already obtained, and how they interrelate.

This wiki exists to harness the collective knowledge of the worldwide SUDEP research community in the hope of focusing and accelerating the effort to better understand and more effectively prevent SUDEP. A massive literature on sudden death in epilepsy and closely related phenomena exists, with many studies having considerable overlap. Many isolated case reports have been published, and considering them collectively increases their informative power. Users of this tool can add entries for articles including links to the articles themselves, contribute to the discussion of articles, add links to the entries on related articles, or post comments. Comparing and contrasting research findings in this way can highlight where open questions exist and potentially target future investigation more effectively. The ultimate aim is better mechanistic insight into the process, which has the potential to reduce SUDEP deaths.

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