Difference between revisions of "Welcome"

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*Colder BW, Wilson CL, Frysinger RC, Harper RM, and Engel J J (1996): [[Interspike intervals during interictal periods in human temporal lobe epilepsy]]
 
*Colder BW, Wilson CL, Frysinger RC, Harper RM, and Engel J J (1996): [[Interspike intervals during interictal periods in human temporal lobe epilepsy]]
 
*Constantin L, Martins JB, Fincham RW, and Dagli RD (1990): [[Bradycardia and syncope as manifestations of partial epilepsy]]
 
*Constantin L, Martins JB, Fincham RW, and Dagli RD (1990): [[Bradycardia and syncope as manifestations of partial epilepsy]]
 +
*Cooper MS, Mcintosh A, Crompton DE, et al. (2016): [[Mortality in Dravet Syndrome]]
 
*Cooper PN (2008): [[Cardiac arrhythmias and SUDEP--Commentary on Hindocha et al.]]
 
*Cooper PN (2008): [[Cardiac arrhythmias and SUDEP--Commentary on Hindocha et al.]]
 
*Corfield DR, Fink GR, Ramsay SC, Murphy K, Harty HR, Watson JD, Adams L, Frackowiak RS, and Guz A(1995): [[Activation of limbic structures during CO2-stimulated breathing in awake man]]
 
*Corfield DR, Fink GR, Ramsay SC, Murphy K, Harty HR, Watson JD, Adams L, Frackowiak RS, and Guz A(1995): [[Activation of limbic structures during CO2-stimulated breathing in awake man]]

Revision as of 20:22, 9 July 2018


An increased risk of sudden death has been reported in patients with epilepsy since the late 1800s, and possibly much earlier (DeToledo et al., 1999; Doherty, 2004). Since the 1990s sudden unexpected (or unexplained) death in epilepsy (SUDEP) has received increasing attention and been recognized as more widespread than previously believed. Despite the increase in awareness, “systematic well funded research remains limited. The medical literature contains much repetition, with effort spent on re-analysing data with substantial methodological limitations,” (Tomson et al., 2008). There is a need for better clinical and basic science studies and improved epidemiological data, and there is also a need for increased knowledge of the findings already obtained, and how they interrelate.

This wiki exists to harness the collective knowledge of the worldwide SUDEP research community in the hope of focusing and accelerating the effort to better understand and more effectively prevent SUDEP. A massive literature on sudden death in epilepsy and closely related phenomena exists, with many studies having considerable overlap. Many isolated case reports have been published, and considering them collectively increases their informative power. Users of this tool can add entries for articles including links to the articles themselves, contribute to the discussion of articles, add links to the entries on related articles, or post comments. Comparing and contrasting research findings in this way can highlight where open questions exist and potentially target future investigation more effectively. The ultimate aim is better mechanistic insight into the process, which has the potential to reduce SUDEP deaths.

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