Effect upon blood pressure of electrical stimulation of tips of temporal lobes in man

Chapman WP, Livingston KE, and Poppen JL (1950) Effect upon blood pressure of electrical stimulation of tips of temporal lobes in man. J Neurophysiol 13:1 65–71

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• Experiment, from era with different ethical norms, on frontal lobotomy patient. Stimulation of the anterior temporal poles in anesthetized patient led to elevation in BP of more than 60 mm Hg for systolic and more than 40 mm Hg for diastolic. Elevations in blood pressure persisted for 30 s or more after stimulation of temporal poles for 10 s. Stimulation of right temporal pole drove larger increase than stimulation of left pole or of both poles simultaneously. e authors discuss the possible contribution of hypothalamic activation.

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